CONFLICT OF INTEREST STATEMENT All the authors declare that there is no conflict of interest. Supporting Information REFERENCES 1, . Coronavirus envelope protein: current knowledge. Virol J. 2019; 16(1): 69. 2, , , et al. Human respiratory coronavirus HKU1 versus other coronavirus infections in Italian hospitalised patients. J Clin Virol. 2007; 38(3): 244-250. 3, . Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology. Semin Immunopathol. 2017; 39: 529-539.