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Mireia Coma

As seen in: Arthritis Research & Therapy
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Articles by Mireia Coma

Application of systems biology-based in silico tools to optimize treatment strategy identification in Still’s disease

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By Mireia Coma, Christoph Kessel, Cristina Segú-Vergés, Serge Smeets
| Arthritis Research & Therapy Verified
Abstract Background Systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still’s disease (AOSD) are manifestations of an autoinflammatory disorder with complex pathophysiology and significant morbidity, together also termed Still’s disease. The objective of the current study is to set in silico models based on systems biology and investigate the optimal treat-to-target strategy for Still’s disease as a proof-of-concept of the modeling approach.
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In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm

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By Laura Artigas, Anaxomics Biotech, Mireia Coma, Pedro Matos-Filipe
| PLOS
Loading metrics Open Access Peer-reviewed Research Article Laura Artigas, Mireia Coma , Pedro Matos-Filipe, Joaquim Aguirre-Plans, Judith Farrés, Raquel Valls, Narcis Fernandez-Fuentes, Juan de la Haba-Rodriguez, Alex Olvera, Jose Barbera, Rafael Morales, Baldo Oliva , Jose Manuel Mas Laura Artigas, Mireia Coma, Pedro Matos-Filipe, Joaquim Aguirre-Plans, Judith Farrés, Raquel Valls, Narcis Fernandez-Fuentes, Juan de la Haba-Rodriguez, Alex Olvera, Jose Barbera Published: October 2, 2020...
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