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Abstract Genetic risk variants in bipolar disorder (BD) may lead to substantial gene expression changes. Transcriptomic studies employing multiplex BD families are extremely scarce. Here, we performed RNAseq on total mRNA of 31 lymphoblastoid cell lines from a cohort of eight multiplex BD families. We conducted differential gene expression and Weighted Gene Co-expression Network Analysis (WGCNA) for candidate genes and pathways identification.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.