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Theoretical Study of the Rearrangement Reaction in Bisorbicillinoid Biosynthesis: Insights into the Molecular Mechanisms Involved Abstract Bisorbibutenolide and bisorbicillinolide are polyketide compounds with complex skeletons that are formed by the dimerization of sorbicillin. These compounds have long been of interest, with several reports of their biosynthesis, biological activity, and total synthesis.
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