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Objective. Hepatitis B virus (HBV) spontaneous mutations may impact the severity of liver disease. This study aimed to assess the mutations in the pre-core (PC) region in HBV-HIV (human immunodeficiency virus) co-infected patients. Additionally, we explored its association with genotypes and examined the clinical implications. Methods. A total of 100 HBV-HIV co-infected patients and 50 HBV mono-infected patients were included in the study.
Article metrics loading... /content/journal/acmi/10.1099/acmi.0.000927.v4 Download as PowerPoint /deliver/fulltext/acmi/7/8/acmi000927.v4.html?itemId=/content/journal/acmi/10.1099/acmi.0.000927.v4&mimeType=html&fmt=ahah References Hou J, Liu Z, Gu F. Epidemiology and prevention of hepatitis B virus infection. Int J Med Sci 2005; 2:50–57 [View Article] [PubMed] [Google Scholar] Beck J, Nassal M. Hepatitis B virus replication.
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