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Epidemiology/Health Services Research Abstract OBJECTIVE The effect of early-life antibiotic treatment on the risk of type 1 diabetes is debated. This study assessed this question, applying a register-based design in children up to age 10 years including a large sibling-control analysis. RESEARCH DESIGN AND METHODS All singleton children (n = 797,318) born in Sweden between 1 July 2005 and 30 September 2013 were included and monitored to 31 December 2014.
Question Is dog exposure during early life linked to type 1 diabetes risk? Findings In this Swedish nationwide, register-based cohort study including 840 593 children and 1999 diabetes events, no evidence was found for an association between register-derived measures of dog exposure and childhood-onset type 1 diabetes. Meaning Advice on exposing children to animals to lower risk for type 1 diabetes is likely not effective.
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