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Articles by Moran Wang
T-cell engager bispecific antibodies enable T cells to eliminate Multiple Myeloma by targeting tumor CD38 in combination with PD-L1
Abstract Bispecific antibodies have gradually been applied in the treatment of multiple myeloma(MM). The combination of bispecific antibodies targeting CD3 and CD28 mimics the dual-signaling system (antigen signaling and co-stimulatory signaling) of natural T cell activation, thereby significantly enhancing the anti-tumor response of T cells. CD38, a transmembrane glycoprotein, is highly expressed on MM cells and serves as an important surface marker.
Engineered Bio-Navigated Nanobubbles Mediating Xenon Neuroprotection and Neutrophil-Trojan Inflammation Regulation for Sequential Stroke Therapy
Wenjun Zhao and Moran Wang contributed equally to this work. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Data supporting the findings of this study are available from the corresponding author upon request. Supporting Information Filename Description adfm77194-sup-0001-SuppMat.docx10.2 MB Supporting File 1: adfm77194-sup-0001-SuppMat.docx.
Electrokinetic transport regulation at liquid-infused surface by liquid depletion and ion partition
Opens in a new window Opens an external website Opens an external website in a new window This website utilizes technologies such as cookies to enable essential site functionality, as well as for analytics, personalization, and targeted advertising. To learn more, view the following link: Privacy Policy Article Text References Phys. Rev. Fluids 11, 063702– Published 18 June, 2026 ©2026 American Physical Society Username Password Enter a citation
Electrophoresis of Charged Dielectric Droplet With Ion Concentration Polarization Effect
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available in the supporting materials of this article. References 1, , and , Zeta Potential in Colloid Science: Principles and Applications (Academic Press, 1981). 2, Fundamentals of Interface and Colloid Science III: Liquid-Liquid Interfaces (Academic Press, 2000).
SIRT5 Inhibition Impairs Mitochondrial Metabolism and Enhances Venetoclax-Induced Elimination of Acute Myeloid Leukemia Cells
10.1038/s41375-025-02673-9 Post-print Humans, Animals, Leukemia, Myeloid, Acute, Mice, Sirtuins, Sulfonamides, Mitochondria, Bridged Bicyclo Compounds, Heterocyclic, Xenograft Model Antitumor Assays, Antineoplastic Agents, Mice, Inbred NOD, Apoptosis, Tumor Cells, Cultured, Cell Line, Tumor yes Wang, Moran; Zhu, Ruiqi; Small, Donald; et al., "SIRT5 Inhibition Impairs Mitochondrial Metabolism and Enhances Venetoclax-Induced Elimination of Acute Myeloid Leukemia Cells" (2025).
A New Hexaploid Species of Isoetes (Isoetaceae) From Fujian, China, Based on Morphological and Molecular Evidence
1 Introduction Isoetaceae, often referred to as living fossils, are considered to have originated during the Late Devonian (359–383 Ma) (Pigg 1992; Kenrick and Crane 1997). Isoetes Linnaeus (1753: 1100), the sole extant genus within Isoetaceae, is widely distributed and comprises over 200 species worldwide (PPG I 2016; Troia et al. 2016). Up to now, 13 species of Isoetes have been reported in China (Handel-Mazzetti 1923; Palmer 1927; DeVol 1972; Wang et al. 2002; Li et al. 2013; Liu et al.
SIRT5 inhibition impairs mitochondrial metabolism and enhances venetoclax-induced elimination of acute myeloid leukemia cells - Leukemia
Abstract Metabolic reprogramming is a key focus of targeted therapies in acute myeloid leukemia (AML). The mitochondrial sirtuin SIRT5 removes succinyl groups from specific lysines and impacts cell metabolism, but its role in AML tumorigenesis has not been extensively explored. A recent study highlighted that SIRT5 regulates AML cell activity by modulating glutamine metabolism, but its molecular targets in AML remain unclear. This study aims to identify the substrates of SIRT5 in AML.
Intensive Widmannstätten Nanoprecipitates Catalyze SnTe With State‐of‐the‐Art Thermoelectric Performance
1 Introduction Owing to their ability to directly convert waste heat into electricity or operate in reverse, thermoelectric materials hold great promise for power generation and solid-state refrigeration.[1-3] The performance of a thermoelectric device is primarily determined by its energy-conversion efficiency, which is closely linked to the figure of merit of thermoelectric materials, ZT = S2σT/κ,[4] in which, S represents the Seebeck coefficient, σ is the electrical conductivity, T is the...
Gas flow regimes and transition criteria in porous media
Traditional categorization of gas flow regimes in porous media relies phenomenally on Darcy's law, yielding phenomenologically a “pre-Darcy” flow regime and a “post-Darcy” flow regime before and after the linear region, respectively. This study redefines the classification of gas flow regimes by integrating the underlying flow mechanisms, proposing four distinct regimes: the slip regime, the Darcy regime, the inertia regime, and the turbulence regime.
Research on the application and evaluation of Mongolian saddle culture in kumis packaging design based on AIGC
Abstract This study explores the application of generative artificial intelligence technology in the design of cultural and creative products, using kumis packaging design as a case study. It establishes and validates a “human + AI” collaborative design framework oriented by user demands, driven by cultural resources, and supported by artificially intelligent technological tools.
Solvent mixing and ion partitioning effects in spontaneous charging and electrokinetic flow of immiscible liquid-liquid interface
Electrokinetic transport occurs at the two-liquid interfaces due to its inevitably spontaneous charging induced by imbalanced partition and/or specific adsorption. The diffuse feature of the liquid-liquid interface is essential in interpretation of its electrokinetic behavior and the interplay of the two charging mechanisms is strongly dependent on the interfacial physicochemical properties, which are often ignored in previous studies and may lead to the impractical electrokinetic predictions.
Sequence Variation of Candida albicans Sap2 Enhances Fungal Pathogenicity via Complement Evasion and Macrophage M2‐Like Phenotype Induction
Abstract Candida albicans (C. albicans) is an opportunistic pathogen increasingly causing candidiasis worldwide. This study aims to investigate the pattern of systemic immune responses triggered by C. albicans with disease associated variation of Sap2, identifying the novel evasion strategies utilized by clinical isolates. Specifically, a variation in clinical isolates is identified at nucleotide position 817 (G to T).
Large Area High-Performance Bismuth Vanadate Photoanode for Efficient Solar Water Splitting
Large Area High-Performance Bismuth Vanadate Photoanode for Efficient Solar Water Splitting Commercial-scale photoelectrochemical (PEC) water splitting devices have been proved to be cost-competitive with fossil-based fuels. Nevertheless, large-scale PEC water splitting cells with high performance are not-yet to be demonstrated, and controllably scaling up high-performance photoelectrodes still remains challenging.
Correction: Continuous inertial microparticle and blood cell separation in straight channels with local microstructures
a Department of Mechanical, Aerospace, and Nuclear Engineering, Rensselaer Polytechnic Institute (RPI), 110 8th Street, Troy, USA E-mail: chunga6@rpi.edu b School of Aeronautic Science and Engineering, Beihang University, Beijing, China c Department of Engineering Mechanics, School of Aerospace, Tsinghua University, Beijing, China
Continuous inertial microparticle and blood cell separation in straight channels with local microstructures
Fluid inertia which has conventionally been neglected in microfluidics has been gaining much attention for particle and cell manipulation because inertia-based methods inherently provide simple, passive, precise and high-throughput characteristics. Particularly, the inertial approach has been applied to blood separation for various biomedical research studies mainly using spiral microchannels.
Continuous inertial microparticle and blood cell separation in straight channels with local microstructures
Fluid inertia that has conventionally been neglected in microfluidics has been gaining much attention for particle and cell manipulation because inertia-based methods inherently provide simple, passive, precise and high-throughput characteristics. Particularly, the inertial approach has been applied to blood sepration for various biomedical research mainly using spiral microchannels.
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