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Articles by M.T. Svendsen
An App to Improve Adherence to Topical Therapy in Psoriasis
Table 1. Available functions in the 28–day adherence–supporting smartphone application (app) Function Compulsory Optional Daily treatment reminder X Daily information on amount of treatment and number of treatment applicationsa X Symptom ratingb on an interval scale, i.e. itching, pain, inflammation, dryness, scaling, stress and social discomfort X aFoam dispensers had an electronic monitor with a chip registering each time the patient used the dispenser.
Use of topical corticosteroids among Danish patients with psoriasis
Summary Psoriasis is a common chronic inflammatory skin disease, affecting about 2‐4% of the population in Europe. Psoriasis negatively affects patients’ quality of life and is linked to several psoriasis‐associated comorbidities (diseases that occur alongside psoriasis). Topical drugs, which means they are applied directly to the skin, are a recommended first‐line treatment for mild‐to‐moderate psoriasis, but their reported real‐life use is conflicting.
British Journal of Dermatology
Summary 银屑病是一种慢性炎症性皮肤病,在欧洲影响大约 2‐4% 的人群。银屑病对患者的生活质量产生不利影响,且与若干银屑病‐相关合并症(与银屑病同时发生的疾病)相关。局部外用药物意味着它们直接用在皮肤上,是轻中度银屑病的推荐一线治疗,但它们所报告的现实生活使用却是相矛盾的。此研究调查了银屑病患者对于局部外用药物和其他抗银屑病治疗的现实生活使用情况。丹麦研究者们基于全国范围的丹麦卫生注册数据进行了一项药物利用研究,这些数据包括所有在 2005‐2015 年间首次获得银屑病住院诊断且被开具至少一种局部外用药物的 18 岁以上患者(7,743 名患者)的数据。在诊断后对这些患者进行了 3 年随访。在众多发现中,作者们报告称,最频繁使用的局部外用抗银屑病药物是含有皮质类固醇和钙泊三醇的复方药物,占总使用量的 31%。患者在医院诊断前后的局部外用药物使用增多。使用量在地理区域以及个体患者之间也有显著差异,25% 患者使用了 70% 的总局部外用治疗量。抗银屑病局部外用药物的总使用量在此研究期间下降了 19%,同时,一种名为甲氨蝶呤的药物的使用(通过片剂或注射液形式使用)则增高了...
British Journal of Dermatology
银屑病是一种常见慢性皮肤病,会导致红色鳞屑状斑块 (皮肤斑片), 通常位于膝部、肘部、头皮和躯干。银屑病可能对患者的生活质量造成负面影响, 并因医疗保健费用、误工等带来额外的“社会经济负担”。局部外用卡泊三醇和皮质类固醇是轻度至中度银屑病的推荐一线治疗, 但很多患者因众多不同原因并不按处方使用这些乳膏或软膏。这项研究调查了使用智能手机患者支持应用 (apps) 能否改善患者局部外用 (用于皮肤) 药物 (皮肤泡沫样卡泊三醇/丙酸倍他米松复方制剂) 的使用, 并额外降低银屑病的严重程度和改善短期和长期生活质量。丹麦皮肤科医生在丹麦 Odense 大学医院皮肤科进行了一项实验。纳入134 名患者, 这些患者被分配使用药物 (66 名患者) 或使用药物+来自 app 的支持 (68 名患者) 共计 4周。这种 app 每天提供一次强制治疗提醒, 还可以通过安装在泡沫给药器顶部的电子监测芯片监测患者是否正在使用他们的药物。通过蓝牙®将这些信息同步到患者的智能电话中。91% 患者在半年期间返回接受所有随访。这项对照试验显示, 使用此 app 的患者在 4 周期间的药物使用显著改善,...
Testing an adherence‐improving app for patients with psoriasis
Psoriasis is a common chronic inflammatory skin disease which causes red, scaly plaques (patches of skin), often on the knees, elbows, scalp and trunk. Psoriasis can have a negative impact on patients’ quality of life, and additionally creates a ‘socioeconomic burden’ due to healthcare costs, time off work, etc.
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