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Articles by Mujeeb U. Shad
Recent Developments in Pharmacotherapy of Depression: Bench to Bedside
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Neurobiological Correlates of Psilocybin Response in MDD
ABSTRACT Objective: To synthesize the neurobiological basis of brain-resetting effects of psilocybin and identify neuroimaging correlates of psilocybin response in depressed patients. Data Sources: MEDLINE(R), Embase, APA PsycINFO, Cochrane, and CINAHL were systematically searched on June 3, 2022, with no date restrictions using the following string: (psilocybin) AND (psychedelics) AND (MRI) OR (fMRI)) OR (PET)) OR (SPECT)) OR (imaging)) OR (neuroimaging)).
Recent Developments in Pharmacotherapy of Depression: Bench to Bedside
Abstract : For the last 70 years, we did not move beyond the monoamine hypothesis of depression until the approval of the S-enantiomer of ketamine, an N-methyl-D-aspartate (NMDA) receptor blocker and the first non-monoaminergic antidepressant characterized by rapid antidepressant and antisuicidal effects. A similar profile has been reported with another NMDA receptor antagonist, dextromethorphan, which has also been approved to manage depression in combination with bupropion.
Seventy Years of Antipsychotic Development: A Critical Review
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Mujeeb U.
High-Dose Therapy in Treatment-Refractory Psychosis: A Retrospective Study
ABSTRACT Objective: To examine the impact of antipsychotic dose adjustments (mainly reduction) on the efficacy and tolerability of antipsychotic medications (APMs) to facilitate hospital discharge in long-term hospitalized forensic patients with treatment-refractory psychosis.
Different Modalities of Transcranial Magnetic Stimulation to Manage Schizophrenia
ABSTRACT Objective: To analyze all current literature related to different transcranial magnetic stimulation (TMS) modalities in the management of schizophrenia symptoms and compare the main controversies in the outcome measures.
Underuse and Suboptimal Use of Clozapine in Treatment-Refractory Schizophrenia
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