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N. Afrin

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Articles by N. Afrin

The evolution to hepta-refractory myeloma involves sequential loss of CD38, BCMA and GPRC5D - Leukemia

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By C. Riedhammer, M. Truger, H. Lee, M. Meggendorfer, S. Hutter, H. Konrad Muller, J. Mersi, SK Kadel, T. Buchwald, R. Kosch, M. Helal, N. Afrin, A. Rosenwald, E. Gerhard-Hartmann, A. Brioli, J. Krönke, T. Haferlach, C. Haferlach, KC Weisel, P. Neri, H. Einsele, KM Kortüm, JM Waldschmidt, N. Bahlis, N. Weinhold, L. Rasche
| Nature Verified
Abstract Multiple myeloma (MM) resistant to CD38 antibodies, two immunomodulatory drugs (IMiDs), two proteasome inhibitors (PIs), and both BCMA- and GPRC5D-directed immunotherapies defines hepta-refractory MM, a novel end-stage entity. In a multi-center cohort of 37 patients, median overall survival was 12.8 months, with progression-free survival across salvage therapy lines of only 2.7–3.7 months.
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Depression, falls, and fractures

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By N. Afrin, R. T. Sund, R. Honkanen, H. Koivumaa-Honkanen
| link.springer.com
This is a preview of subscription content, log in to check access. References 1. Edwards MH, Jameson K, Denison H, Harvey NC, Sayer AA, Dennison EM, Cooper C (2013) Clinical risk factors, bone density and fall history in the prediction of incident fracture among men and women. Bone 52:541–547 2. Koivumaa-Honkanen H, Kaprio J, Honkanen R, Viinamäki H, Koskenvuo M (2004) Life satisfaction and depression in a 15-year follow-up of healthy adults. Soc Psychiatry Psychiatr Epidemiol 39:994–999 3.
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Role of musculoskeletal disorders in falls of postmenopausal women

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By N. Afrin
| link.springer.com
We aimed to investigate the role of musculoskeletal disorders (MSDs) as risk factors for falls among postmenopausal women. Our results indicate that MSDs are common and are associated with increased falling risk, especially nonslip falls. Excess number of falls due to MSDs is greater than that due to any other disease class. Falls are a major public health problem worldwide. The aim of the study was to investigate the role of MSDs as risk factors for falls among postmenopausal women.
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