Self-assembly and self-delivery pure nanodrug of dihydroartemisinin for tumor therapy and mechanism analysis Yawei Li, Wei Zhang, Naiyuan Shi, Wenqing Li, Junxia Bi, Xianmin Feng, Nianqiu Shi, Wenhe Zhu and Zhigang Xie Abstract Dihydroartemisinin (DHA), a plant-derived natural product, has recently been proved to be an effective therapeutic agent for cancer treatment. Nevertheless, the poor water solubility and low bioavailability of DHA seriously impede its clinical application.
