Patterns in the Economic Burden of Acute Kidney Injury in Hospitalized Children, 2019-2021 Introduction Pediatric acute kidney injury (AKI) is common, especially in hospitalized children, its incidence being 18.7% overall and 24.4% among critically ill patients.1 Children with AKI have increased odds of higher length of stay (LOS), death, hypertension, proteinuria, and chronic kidney disease.1,2 Development of AKI increases health care costs and resource use burden.