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To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Introduction: The National Cancer Survivorship Initiative has identified the need for breast cancer follow-up to move towards self-care, with improved patient education and support. In response, Hull and East Yorkshire Hospitals NHS Trust developed a survivorship programme, combining mammographic surveillance with holistic needs assessment (HNA).
IntroductionThe thymus is essential for the prevention of autoimmunity through the induction of T cell tolerance and the generation of FoxP3+ regulatory T cells (Tregs). Thymocytes expressing a functional TCR are positively selected by interacting with cortical thymic epithelial cells (TECs) (cTECs), after which they migrate and interact with tissue-specific Ags (TSAs) presented on medullary TECs (mTECs) and dendritic cells.
Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity Natalie A. Roberts, Brian D. Adams, Nicholas I. McCarthy, Reuben M. Tooze, Sonia M. Parnell, Graham Anderson, Susan M. Kaech, Valerie Horsley The Journal of Immunology July 12, 2017, ji1600941; DOI: 10.4049/jimmunol.1600941
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