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Patents on Small-Molecule Drugs Approved by the US Food and Drug Administration, 1990-2019 Abstract Importance Patent protection allows pharmaceutical companies to charge high prices for prescription drugs during periods of market exclusivity, and their expiration usually defines when generic competitors can enter the US market. Patents on drug active ingredients are classified as primary patents, while patents on formulations, methods of use, and delivery devices are nonprimary.
Abstract Online sex advertisements (sex ads) have been linked to many U.S. sex trafficking cases. However, since the closure of the dominant website, Backpage.com (Backpage), many competing sites have emerged that are hosted in countries where U.S. law enforcement organizations have no jurisdiction. Although the online ecosystem has changed significantly, very little research uses data from sites other than Backpage, and even less uses data from multiple sites.
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