Loading metrics Open Access Peer-reviewed Research Article Citation: Tugui N, Islam SS, Heath DD (2026) Gene transcriptional profiling of osmoregulatory stress response in salmonids: Development and assessment of high-throughput multispecies assays. PLoS One 21(10): e0360513. https://doi.org/10.1371/journal.pone.0360513 Editor: Arnar Palsson, University of Iceland, ICELAND Received: March 28, 2026; Accepted: September 28, 2026; Published: October 9, 2026 Copyright: © 2026 Tugui et al.