Abstract Pregnancy is a multidimensional process that leads to significant changes in a woman’s body image and sexual life. This study aimed to examine the relationships among pelvic floor dysfunction, body image perception, and sexual desire in pregnant women in the third trimester, and to evaluate the predictive role of these variables on sexual desire. This cross-sectional study included 209 pregnant women in their third trimester (Mean age = 28.63, SD = 5.88) in the study.