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2. Materials and Methods 2.1. Study Subjects We conducted a retrospective analysis on tissues from two independent cohorts of adult patients with newly diagnosed, IDH wild type GBM. The patients in the Hannover cohort received treatment at the Department of Neurosurgery, Nordstadt Hospital Hannover from 2004 to 2014 while in the Magdeburg cohort, the patients were treated at the Department of Neurosurgery, University Hospital Magdeburg between 2005 and 2018.
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