We have recently read the case report from Dine et al. entitled “Hematological ABP: Interest of New Generation Sequencing Methods (NGS) to Study Suspicious Fluctuations in Erythropoiesis” [1]. We believe that this paper contains fundamental misunderstandings of how the Athlete Biological Passport works, combined with an incomplete assessment of available evidence supporting a functional role of particular genetic variants, resulting in speculative and potentially misleading conclusions.
