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To explore putative associations between specific variants in either the glutathione S-transferase (GST), haptoglobin (HP), or uridine 5?-diphospho-glucuronosyltransferase 1A1 (UGT1A1) genes and clinically important phenotypes in sickle cell anaemia (HbSS). Three hundred and seventy-one HbSS participants were recruited from the Sickle Cell Clinic of the Sickle Cell Unit at the University of the West Indies, Kingston, Jamaica.
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