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What's is already known about this topic? ◦ Accurate fetal fraction (FF) quantification is essential for reliable non-invasive prenatal screening (NIPS) outcomes. ◦ FF quantification via next-generation sequencing (NGS) varies by algorithm, leading to inconsistent results across laboratories. ◦ An unmet need for fast and accurate FF quantification is emerging for existing and new diagnostic applications. What does this study add?
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