ORIGINAL ARTICLE Arne N. Akbar Corresponding Author E-mail address: a.akbar@ucl.ac.uk Division of Infection and Immunity, University College London, UK Corresponding authors Núcleo de Doenças Infecciosas/ Núcleo de Biotecnologia, Universidade Federal do Espirito Santo – UFES. Av. Marechal Campos, 1468 ‐ Maruípe, Vitória – Brazil. Cep 29043‐900 Division of Infection and Immunity, The Rayne Building, University College London. 5, University Street, London WC1E 6JF.