Urea cycle disorder treatment involves managing rare genetic conditions in which the body lacks the enzymes needed to break down ammonia, leading to toxic accumulation. The goal of treatment is to lower blood ammonia levels. The main treatment options for urea cycle disorders include amino acid supplements, sodium phenylbutyrate, glycerol phenylbutyrate, sodium benzoate, and others. Amino acid supplements provide one or more of the nine essential amino acids that the body cannot produce naturally.