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To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. FiguresThere is equipoise with regards to the optimal prosthesis for aortic valve infective endocarditis (IE). A systematic review and meta-analysis was performed to compare outcomes between homograft and conventional prosthesis for aortic valve IE.
Chronic pain is frequently associated with hypersensitivity of the nervous system, and drugs that increase central inhibition are therefore a potentially effective treatment. Benzodiazepines are potent modulators of GABAergic neurotransmission and are known to exert antihyperalgesic effects in rodents, but translation into patients are lacking. This study investigates the effect of the benzodiazepine clobazam in chronic low-back pain in humans.
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