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1 Introduction Thyroblastoma is a newly recognized entity, included in the 5th Edition WHO Classification of Endocrine and Neuroendocrine Tumors, and is molecularly defined by DICER1 mutations [1]. Histologically, it shows complex multilineage features, including fetal-type thyroid follicles, fetal-type glands, a primitive blastemal component, and spindle cell stroma with possible rhabdomyoblastic differentiation [1].
Abstract High-throughput 2D and 3D scanning electron microscopy, which relies on automation and dependable control algorithms, requires high image quality with minimal human intervention. Classical focus and astigmatism correction algorithms attempt to explicitly model image formation and subsequently aberration correction.
This case report describes a rare case of nodal low grade serous pelvic neoplasia. Together with histological correlation, it illustrates previously undocumented cytomorphological features and also discusses important differential diagnosis and potential pitfalls for misdiagnosis.
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