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Articles by P. Stephen Patrick
179 CT-visible microspheres enable in vivo tracking of biomaterial distribution after ultrasound-guided intramyocardial injection
179 CT-visible microspheres enable in vivo tracking of biomaterial distribution after ultrasound-guided intramyocardial injection Free Annalisa Bettini, P. Stephen Patrick, Richard Day, Daniel Stuckey University College London, London, UK Abstract Efficacy of cell therapies are often diminished by low cell retention.
A blueprint for translational regenerative medicine
Abstract The past few decades have produced a large number of proof-of-concept studies in regenerative medicine. However, the route to clinical adoption is fraught with technical and translational obstacles that frequently consign promising academic solutions to the so-called “valley of death.” Here, we present a proposed blueprint for translational regenerative medicine.
Preclinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies
Abstract Regenerative medicine therapies hold enormous potential for a variety of currently incurable conditions with high unmet clinical need. Most progress in this field to date has been achieved with cell-based regenerative medicine therapies, with over a thousand clinical trials performed up to 2015. However, lack of adequate safety and efficacy data is currently limiting wider uptake of these therapies.
Surface Radio-Mineralisation Mediates Chelate-free Radiolabelling of Iron Oxide Nanoparticles
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Chemically Treated 3D Printed Polymer Scaffolds for Biomineral Formation
Additive manufacturing, or three-dimensional (3D) printing, presents a number of interesting avenues for composite material manufacture beyond mostly monolithic prototyping because of the various stepwise methods of material deposition and processing employed at micron scale accuracy in a 3D space. 1.
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