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Articles by Pan Ren
Dose–response relationship between growth hormone treatment and the development of scoliosis in children with short stature
Abstract Background We sought to investigate whether growth hormone (GH) treatment increases the risk of scoliosis in children with short stature and analyse a dose-response relationship. Methods A retrospective cross-sectional and cohort study design was used. The cross-sectional study included 1160 children with short stature (355 and 805 in the GH-exposed and non-exposed groups, respectively). The scoliosis prevalence was compared.
Machine learning–guided Huanglian Jiedu decoction targets STING in periodontitis-induced Alzheimer’s Disease - npj Digital Medicine
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder increasingly associated with peripheral inflammatory conditions such as chronic periodontitis (CP); however, the molecular mechanisms linking these conditions remain poorly understood. Here, we investigated the therapeutic effects of Huanglian Jieddu Decoction (HLJDD) on CP-induced AD using an integrative machine learning-guided multi-omics approach.
Influence of Mechanical Polishing on Cyclic Oxidation Behavior of (Ni,Pt)Al Coatings at 1100°C
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A Low‐Loss High‐Frequency Transmission Line Structure for Ceramic Substrate
References 1, , , , and , “ Chip Last Fan-Out Packaging for Millimeter Wave Application,” In Proceedings - Electronic Components and Technology Conference, Institute of Electrical and Electronics Engineers Inc. (IEEE, 2016), 1303–1308, https://doi.org/10.1109/ECTC.2016.197.
Swallowing rehabilitation of patients undergoing T‐tube implantation for the treatment of laryngotracheal stenosis
DATA AVAILABILITY STATEMENT All data generated or analysed during this study are included in this article. Further enquiries can be directed to the corresponding author.
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis
Abstract Sepsis is a leading cause of in-hospital mortality resulting from a dysregulated response to infection. Novel immunomodulatory therapies targeting macrophage metabolism have emerged as an important focus for current sepsis research. However, understanding the mechanisms underlying macrophage metabolic reprogramming and how they impact immune response requires further investigation.
A new ligand-regulated strategy of highly mesoporous metal-organic framework assembled in ionic liquid/ethanol solvent
A new ligand-regulated strategy of highly mesoporous metal–organic framework assembled in ionic liquid/ethanol solvent Xiaoxue Ma, Pan Ren, Donglu Fu, Xinchen Kang, Minghua Jing, Xinxin Sang, Dawei Fang and Zongren Song Abstract The hierarchical porous metal–organic frameworks catalysts were synthesized by ligand regulation in ionic liquid/ethanol system for the first time. The porosity and morphology could be tuned by the mass fraction of ionic liquid/ethanol and ligand.
Recent Advances in Inorganic Material Thermoelectrics
Thermoelectrics is a research area that focuses the efforts on the development of high performance materials for direct thermal and electrical energy conversion in power generation and solid-state cooling. Ever since Ioffe’s inference in 1950s that heavily doped semiconductors make best thermoelectrics, inorganic semiconductors and semimetals have remained the cornerstone of high performance thermoelectric materials.
Angewandte Chemie International Edition
A nearly‐30‐year‐old unanswered synthetic puzzle, astellatol, has been solved in an enantiospecific manner. The highly congested pentacyclic skeleton of this rare sesterterpenoid, which possesses a unique bicyclo[4.1.1]octane motif, ten stereocenters, a cyclobutane that contains two quaternary centers, an exo‐methylene group, and a sterically encumbered isopropyl trans‐hydrindane motif, makes astellatol arguably one of the most challenging targets for sesterterpenoid synthesis.
Back Cover: Total Synthesis of Astellatol (Angew. Chem. Int. Ed. 13/2018)
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Total Synthesis of Astellatol
AbstractChinese paper cutting is a long-standing tradition in China, and often used to decorate doors and windows during the Spring Festival. The Chinese character ? means blessing and happiness and the character ? means spring. With this backdrop, J. Xu et?al. present in their Communication (DOI: 10.1002/anie.201800167) the first enantiospecific synthesis for a three-decade-old synthetic challenge, astellatol.
Angewandte Chemie International Edition
A nearly-30-year-old unanswered synthetic puzzle, astellatol, has been solved in an enantiospecific manner. The highly congested pentacyclic skeleton of this rare sesterterpenoid, which possesses a unique bicyclo[4.1.1]octane motif, ten stereocenters, a cyclobutane that contains two quaternary centers, an exo-methylene group, and a sterically encumbered isopropyl trans-hydrindane motif, makes astellatol arguably one of the most challenging targets for sesterterpenoid synthesis.
Partial Indium solubility induces chemical stability and colossal thermoelectric figure of merit in Cu2Se
High thermoelectric figure of merit, ZT~2.1 at 1000 K, have been reported in Cu2-xSe-based materials. However, their deployments in operational devices have been hampered by chemical instability and low average ZT (ZTave) values.
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