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Pascal Sirvent

France
As seen in: Nature
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Articles by Pascal Sirvent

Totum-63, a plant-based polyphenol-rich extract, in prediabetes or early-stage type 2 diabetes: an international, multicenter, randomized controlled trial

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By Vivien Chavanelle, Yolanda F. Otero, Bruno Pereira, Nathalie Boisseau Verified, Bruno Guigas, Sébastien Peltier, Florian Le Joubioux, Thierry Maugard, Samy Hadjadj, Pascal Sirvent, André Marette, Murielle Fayat Cazaubiel, Jean-Marie Bard, Véronique Sapone, Annie Bouchard-Mercier, Maxime Bargetto
| Nature Verified
Abstract This multicenter, parallel-arm, superiority, randomized, double-blind, placebo-controlled study evaluates the efficacy of Totum-63 (T63), a polyphenol-rich blend of plant extracts, in improving fasting plasma glucose (FPG) in individuals with prediabetes or early-stage type 2 diabetes (T2D).
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Effect of a polyphenol-rich extract on LDL cholesterol in mild to moderate hypercholesterolemia: a randomized, double-blind, placebo-controlled trial - European Journal of Clinical Nutrition

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By Cédric Langhi, Marie Vallier, Vivien Chavanelle, Pascal Sirvent
| Nature Verified
Abstract Hypercholesterolemia is a well-known risk factor for cardiovascular disease. This clinical trial evaluated the effects of TOTUM-070, a polyphenol-rich blend of plant extracts, on lipid metabolism in individuals with moderate hypercholesterolemia. This was a 6-month, multicenter, randomized, double-blind, placebo-controlled trial.
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