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Articles by Patrick Arsenault
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
Abstract Tyrosine kinase inhibitors (TKIs) targeting anaplastic lymphoma kinase (ALK) have transformed the treatment landscape of ALK fusion-positive non-small-cell lung carcinoma (ALK-positive NSCLC), but the limited options for patients who progress on approved TKIs highlight a continued need for an orthogonal therapeutic approach1,2. TRI-611 is a potent, brain-penetrant molecular glue degrader of ALK fusion proteins with the potential to address this need.
Top 5 Reasons Non‑Emergency Calls Are Overwhelming PSAPs—and How AI Can Help
What This Means for PSAP Operations Non-emergency calls aren’t “noise”—they’re legitimate community needs. But when they flow through the same front door as life-safety emergencies, they create queue congestion, burnout, and avoidable delays. AI-based automated response solutions give PSAPs a way to separate routine from urgent at the point of entry, document interactions automatically, and route callers to the right help faster.
WMass field hockey: Megan Carey lifts South Hadley past Belchertown in overtime
Published: 11/1/2019 10:21:30 PM Modified: 11/1/2019 10:21:15 PM SOUTH HADLEY — It only took 43 seconds of overtime to decide a Western Massachusetts Division 2 Field Hockey Tournament quarterfinal matchup that had otherwise been played to a stalemate through regulation. South Hadley freshman Megan Carey scored the game-winning goal to help the fourth-seeded Tigers advance, 2-1, over No. 5 Belchertown Friday night. “It was crazy,” Carey said.
10 Reasons Why Building Multicultural Competence in College Matters
Japanese students on Columbia College promoting an upcoming multicultural competence development activity. Published on February 1, 2017February 1, 2017 • 9 Likes • 0 Comments Patrick Arsenault, RCICFollow let's chat about how we can better integrate international students and immigrants in Canada Increasingly, colleges and universities put in place diversity awareness programs, multicultural curriculum requirements and intercultural initiatives.
Hatfield native Devon (Vachula) Elliott to be inducted into Clark University Athletics Hall of Fame
Published: 5/10/2019 9:05:58 PM Modified: 5/10/2019 9:05:45 PM NORTHAMPTON — When Devon (Vachula) Elliott got a call from Clark University Athletic Director Patricia Cronin in January, she was caught off guard to find out she was selected for induction into the university’s hall of fame. Elliott, who graduated in 2000, was happy to be honored for her field hockey achievements, but was just as pleasantly surprised to find out that it was her two sons who sent in her nomination.
Hopkins Academy, Mount Everett seek first WMass Division 4 girls basketball title
Published: 3/8/2019 9:33:32 PM HADLEY — When Hopkins Academy and Mount Everett faced off earlier this season, neither team likely imagined they’d meet again in the Western Massachusetts Division 4 girls basketball championship with history on the line. Last year, Mount Everett was knocked out of the tournament as the No. 5 seed by No. 1 Monson in the semifinal round. This year as the No. 4 seed, the Eagles upset No. 1 Monson, 61-50, in Monday’s semifinal to make it to Saturday’s final.
The Recorder - UMass Dayton
SPRINGFIELD — The season may have come to an end Tuesday night for Frontier Regional girls basketball team in its 35-25 loss to Sabis, but the season of improvement wasn’t lost on the young team. The 10th-seeded Red Hawks (10-11) couldn’t complete the Western Massachusetts Division 3 Tournament first-round upset over No. 7 Sabis (11-10), which will go on to face Hoosac Valley in the quarterfinals.
The Recorder - Greenfield hockey falls to Amherst, suffers first loss of season
Kouji Ishida, right, of Amherst Regional, moves the puck ahead of Doug Hanieski, of Greenfield, Wednesday, Jan. 30, 2019 at Orr Rink in Amherst. —STAFF PHOTO/JERREY ROBERTS Gio Rivera, front, of Amherst Regional, moves the puck against Greenfield, Wednesday, Jan. 30, 2019 at Orr Rink in Amherst. —STAFF PHOTO/JERREY ROBERTS Greenfield’s Bryan Baumann, right, of Greenfield, moves the puck while defended by Nick Paul, of Amherst Regional, Wednesday, Jan. 30, 2019 at Orr Rink in Amherst.
HS indoor track: Athletes gear up for postseason
Bradyn Cote, of South Hadley, runs the mile during a PVIAC meet Friday, Jan. 25, 2019 at Smith College. —STAFF PHOTO/JERREY ROBERTS Darius Robinson, left, of Amherst, and Jonas Clarke, of Amherst Regional, are neck-and-neck in the 55-meter dash during a PVIAC meet Friday, Jan. 25, 2019 at Smith College. —STAFF PHOTO/JERREY ROBERTS Emile Bensidrine, of Northampton, runs the mile during a PVIAC meet Friday, Jan. 25, 2019 at Smith College.
The Recorder - Two-time national champion Amherst opens women’s basketball season with new expectations
AMHERST — Over the last two seasons, winning has become an expectation for the Amherst College women’s basketball team. The expectation is not only that the Mammoths win, but that they win every game. Amherst has repeated as Division III national champions with a 33-0 record each year. Still, the nature of college athletics is that there’s a lot of turnover year to year. The Mammoths graduated three seniors and lost four of their five 6-footers, including Final Four MVP Emma McCarthy.
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