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Articles by Patrick Asbach
Automated segmentation and quantification of histological liver features for MASH/MASLD scoring
Abstract The increasing global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) including metabolic dysfunction-associated steatohepatitis (MASH) creates an urgent need for objective histopathological assessment. Conventional histological approaches are time-consuming and subjective. Therefore, we propose a fully automated, deep-learning-based pipeline for the segmentation and characterisation of histological liver features of MASH/MASLD.
Oncological Safety of MRI-Informed Biopsy Decision-Making in Men With Suspected Prostate Cancer
Key Points Question Is it safe to omit biopsy following negative magnetic resonance imaging (MRI) results in men with clinically suspected prostate cancer? Findings In this cohort study involving 593 biopsy-naive men, 48% had negative MRI results, 86% of whom avoided biopsy over 3 years. After 3 years of programmatic monitoring, clinically significant prostate cancer was detected in 4% of men with negative MRI results who exhibited an ongoing elevated clinical risk.
Are upgraded DCE-positive PI-RADS 3 lesions truly suspicious for clinically significant prostate cancer?
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Permian metabolic bone disease revealed by microCT: Paget’s disease-like pathology in vertebrae of an early amniote
Loading metrics Open Access Peer-reviewed Research Article Yara Haridy , Florian Witzmann, Patrick Asbach, Robert R. Reisz Yara Haridy, Florian Witzmann, Patrick Asbach, Robert R. Reisz Published: August 7, 2019 https://doi.org/10.1371/journal.pone.0219662 Figures Abstract Bone remodeling is an essential physiological process in growth and healing. In modern systems deviations from normal bone physiology in the form of pathologies aid in the understanding of normal bone metabolism.
Triassic Cancer-Osteosarcoma in a 240-Million-Year-Old Stem-Turtle
Paleopathology, the study of ancient disease, is a vital way by which we understand the evolution of pathogens, immune systems, healing physiology, and ultimately the environment.
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