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Patrick Schmerer

As seen in: Science Magazine, BioRxiv
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Articles by Patrick Schmerer

Low Density Lipoprotein Receptor-Related Protein 1 (LRP1) as an auxiliary host factor for RNA viruses including SARS-CoV-2

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By Stephanie Devignot, Tim Wai Sha, Thomas Burkard, Patrick Schmerer
| BioRxiv
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Identification of SARS-CoV-2-induced pathways reveals drug repurposing strategies

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By Namshik Han, Konstantinos Tzelepis, Woochang Hwang, Patrick Schmerer
| Science Magazine Verified
Abstract The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) necessitates the rapid development of new therapies against coronavirus disease 2019 (COVID-19) infection. Here, we present the identification of 200 approved drugs, appropriate for repurposing against COVID-19. We constructed a SARS-CoV-2–induced protein network, based on disease signatures defined by COVID-19 multiomics datasets, and cross-examined these pathways against approved drugs.
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