1. Introduction Tuberculosis (TB) disease, caused by bacteria of the Mycobacterium tuberculosis complex (MTBC), is a major global public health problem with drug resistance making its control difficult (World Health Organization, 2021). The available vaccine, Bacillus Calmette-Guérin (BCG), has limited efficacy and recent attempts to develop more productive vaccines have been unsuccessful, in part due to the insufficient understanding of host-pathogen interactions (Sable et al., 2019).