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Abstract The ER membrane complex (EMC) facilitates insertion of integral membrane proteins into the endoplasmic reticulum (ER) lipid bilayer. Recent years have seen significant progress in understanding the structural aspects of EMC, but the identity of EMC-client proteins and EMC’s functional roles throughout evolution remain less well understood.
Na reunião anual da Associação Europeia de Estabelecimentos de Ensino de Medicina Veterinária, que ocorreu no final de maio em Paris, a frase que mais ecoou foi que precisamos de mais médicos veterinários. Os veterinários são um elemento-chave no conceito de “Uma Só Saúde”.
Abstract : Simple Summary Head and neck cancer (HNC) incidence has been steadily increasing since the 1990s. While the multimodal treatment approach for localized HNC is well established and renders a good treatment response, this is not the case for advanced or recurrent/metastatic HNC. Most patients present HNC at an advanced stage at the time of diagnosis, and the lack of effective treatment results in the death of half of patients diagnosed with advanced or recurrent/metastatic HNC.
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