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Articles by Peter Bager
Acute SARS-CoV-2 infection and self-reported post-acute cognitive dysfunctions from the Danish EFTER-COVID survey
Abstract The extent and burden of post-acute cognitive dysfunctions following SARS-CoV-2 infection is uncertain. 25,485 SARS-CoV-2 test-positive and 25,032 test-negative individuals were repeatedly asked to score symptoms of subjective cognitive deficits 2 to 18 months after test using the “Cognitive complaints in bipolar disorder rating assessment” (COBRA) tool.
The hospital and mortality burden of COVID-19 compared with influenza in Denmark: a national observational cohort study, 2022-24
Introduction Although the COVID-19 pandemic is subsiding, infections with SARS-CoV-2 persist. These infections result in a substantial hospital and mortality burden that is moving towards a pattern resembling that of seasonal influenza.
Association between biosecurity and zoonotic transmission of LA-MRSA CC398 from industrial pig farms to farm workers and their household members
Abstract Background Zoonotic transmission of livestock-associated methicillin-resistant Staphylococcus aureus clonal complex 398 (LA-MRSA CC398) from industrial pig farms to farm workers and their household members and secondary transmission to elderly and immunocompromised persons has led to a growing number of serious infections and even death.
The post-pandemic hospital and mortality burden of COVID-19 compared with influenza: A national cohort study in Denmark, May 2022 to June 2024
The authors have declared no competing interest. This study was conducted as part of the Danish COVID-19 surveillance with governmental financial support. I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Relative vaccine protection, disease severity, and symptoms associated with the SARS-CoV-2 omicron subvariant BA.2.86 and descendant JN.1 in Denmark: a nationwide observational study
Research in context Evidence before this study The omicron BA.2.86 SARS-CoV-2 subvariant, and in particular its descendant JN.1, have spread rapidly around the world, consistent with their greater immune escape compared with other variants, as evidenced in virological studies. However, vaccine protection against, and the severity of infections with, these new subvariants remain unclear.
Cohort profile: EFTER-COVID - a Danish nationwide cohort for assessing the long-term health effects of the COVID-19 pandemic
Introduction Soon after the start of the SARS-CoV-2 pandemic, repeated reports of patients with lingering post acute symptoms started to appear.1 2 A plethora of different possible post acute symptoms were reported,3 but due to the lack of appropriate control groups,1 2 it was unclear whether all symptoms were related to infection with SARS-CoV-2, or if some were of other unrelated causes.
The effectiveness of pollen allergen immunotherapy on allergic rhinitis over 18 years: A national cohort study in Denmark
AIT allergen immunotherapy AR allergic rhinitis GBM grass-birch-mugwort GP general practitioner. INS intranasal corticosteroid inhaler NS nasal inhaler 1 INTRODUCTION Allergic rhinitis (AR) is a common chronic upper respiratory tract illness, characterized by running nose, sneezing, nasal blockage, as well as itchy, and watery eyes. In the majority, these symptoms are caused by IgE-mediated hypersensitivity to plant pollen, and thus triggered in pollen seasons.
Eurosurveillance | A standardised protocol for relative SARS-CoV-2 variant severity assessment, applied to Omicron BA.1 and Delta in six European countries, October 2021 to February 2022
Home Eurosurveillance Volume 28, Issue 36, 07/Sep/2023 Article Euroroundup Open Access http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2023.28.36.2300048 Like 0 Access full text Article View Affiliations Hide Affiliations Affiliations: 1 MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom 2 Statens Serum Institut, Copenhagen, Denmark 3 Health Directorate, Luxembourg, Luxembourg 4 European Centre for Disease Prevention and Control, Stockholm, Sweden 5...
Covid-19 and post-acute sick leave: a hybrid register and questionnaire study in the adult Danish population
Study design In this cohort study, we merged nationwide survey- and register data. In Denmark, all residents are assigned a unique identifier (the CPR-number) in the Danish Civil Registration System, and this number is commonly used to link individual-level data from varying data sources. A summary of the characteristics of our study population and which variables we used from survey responses and register data are presented in Figure 1.
Conflicting COVID-19 excess mortality estimates
Excess mortality is an important metric summarising COVID-19 disease burden, informing public health policy and future preparedness needs. 1 Vestergaard LS Mølbak K Timely monitoring of total mortality associated with COVID-19: informing public health and the public. Euro Surveill. 25: 2001591 However, separating the deaths that occurred from COVID-19 versus those from all other causes is challenging. Essentially, the unknowns are the counterfactual, should an infection wave not have happened.
Risk of reinfection, vaccine protection, and severity of infection with the BA.5 omicron subvariant: a nation-wide population-based study in Denmark
Summary Background Estimates of immunity and severity for the SARS-CoV-2 omicron subvariant BA.5 are important to assess the public health impact associated with its rapid global spread despite vaccination. We estimated natural and vaccine immunity and severity of BA.5 relative to BA.2 in Denmark, a country with high mRNA-vaccination coverage and free-of-charge RT-PCR testing.
Post-acute symptoms four months after SARS-CoV-2 infection during the Omicron period: a nationwide Danish questionnaire study
Abstract Abstract Objectives To evaluate the effects of the Omicron variant on the post-acute symptoms, four months after infection with SARS-CoV-2. Design A nationwide questionnaire study. Setting Denmark. Participants 44,004 individuals aged 15 years or older with either a SARS-CoV-2 RT-PCR positive test result from the period of Delta dominance (July to November 2021), or a positive or negative RT-PCR test result from the period of Omicron dominance (December 2021 to January 2022).
Risk of hospitalisation associated with infection with SARS-CoV-2 omicron variant versus delta variant in Denmark: an observational cohort study
Summary Background Estimates of the severity of the SARS-CoV-2 omicron variant (B.1.1.529) are crucial to assess the public health impact associated with its rapid global dissemination. We estimated the risk of SARS-CoV-2-related hospitalisations after infection with omicron compared with the delta variant (B.1.617.2) in Denmark, a country with high mRNA vaccination coverage and extensive free-of-charge PCR testing capacity.
Post-acute symptoms, new onset diagnoses and health problems 6 to 12 months after SARS-CoV-2 infection: a nationwide questionnaire study in the adult Danish population
Abstract Background A considerable number of individuals infected with SARS-CoV-2 continue to experience symptoms after the acute phase. More information on duration and prevalence of these symptoms in non-hospitalized populations is needed.
Molecular epidemiology of the SARS-CoV-2 variant Omicron BA.2 sub-lineage in Denmark, 29 November 2021 to 2 January 2022
Home Eurosurveillance Volume 27, Issue 10, 10/Mar/2022 Article Rapid communication Open Access http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.10.2200181 Like 0 Access full text Article Jannik Fonager1,* , Marc Bennedbæk1,* , Peter Bager2 , Jan Wohlfahrt3 , Kirsten Maren Ellegaard4 , Anna Cäcilia Ingham4 , Sofie Marie Edslev4 , Marc Stegger4 , Raphael Niklaus Sieber4 , Ria Lassauniere1 , Anders Fomsgaard1 , Troels Lillebaek5,6 , Christina Wiid Svarrer4 , Frederik...
Hospitalisation associated with SARS-CoV-2 delta variant in Denmark
The SARS-CoV-2 B.1.617.2 (delta) variant was first reported in India in December, 2020, and by July, 2021, was predominant over the B.1.1.7 (alpha) variant in most of Europe due to its higher transmissibility., Infections with the alpha variant have been shown to be more severe than preceding SARS-CoV-2 strains, 3 Nyberg T Twohig KA Harris RJ et al. Risk of hospital admission for patients with SARS-CoV-2 variant B.1.1.7: cohort analysis. BMJ.
Risk of hospitalisation associated with infection with SARS-CoV-2 lineage B.1.1.7 in Denmark: an observational cohort study
Summary Background The more infectious SARS-CoV-2 lineage B.1.1.7 rapidly spread in Europe after December, 2020, and a concern that B.1.1.7 could cause more severe disease has been raised. Taking advantage of Denmark's high RT-PCR testing and whole genome sequencing capacities, we used national health register data to assess the risk of COVID-19 hospitalisation in individuals infected with B.1.1.7 compared with those with other SARS-CoV-2 lineages.
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