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Peter Maye

As seen in: BioRxiv, Texas Medical Center
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Articles by Peter Maye

A Transgenic Bacterial Artificial Chromosome Approach to Identify Regulatory Regions That Direct AMHR2 and Osterix Expression in Müllerian Duct Mesenchyme

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By Rachel Mullen, Daniel Idowu, Peter Maye, Malcolm M Moses
| Texas Medical Center
A transgenic mouse approach using bacterial artificial chromosomes (BAC) was used to identify regulatory regions that direct Müllerian duct expression for Amhr2 and Osterix (Osx, also known as Sp7). Amhr2 encodes the receptor that mediates anti-Müllerian hormone (AMH) signaling for Müllerian duct regression in male embryos. Amhr2 is expressed in the Müllerian duct mesenchyme of both male and female embryos. A ∼147-kb BAC clone containing the Amhr2 locus was used to generate transgenic mice.
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Hair follicle-resident progenitor cells are a major cellular contributor to heterotopic subcutaneous ossifications in a mouse model of Albright hereditary osteodystrophy

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By Patrick McMullan, Qingfen Yang, Peter Maye, Sarah Edie
| BioRxiv
Abstract Heterotopic ossifications (HOs) are the pathologic process by which bone inappropriately forms outside of the skeletal system. Despite HOs being a persistent clinical problem in the general population, there are no definitive strategies for their prevention and treatment due to a limited understanding of the cellular and molecular mechanisms contributing to lesion development.
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