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1. Introduction Macroautophagy (hereafter autophagy) delivers superfluous or damaged cytosolic material, including parts of organelles, for degradation to the lysosome (vacuole). Autophagy and its molecular machinery are highly conserved from yeast to humans and have attracted great medical interest [1,2,3,4]. In S. cerevisiae, which was used in this project, autophagy starts with the de novo assembly of double-membraned phagophores (isolation membranes).
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