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Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description vco13038-sup-0001-Appendix_1.docxWord 2007 document , 433.6 KB Appendix 1 Forest plot showing the partial response in dogs with CTVT treated with vincristine. The means are indicated by squares, with lines representing the 95% confidence interval. A rate of 1% of PR was identified (95% CI: 0%–4%).
1 INTRODUCTION Canine mast cell tumours (MCTs) are the most common integumentary malignancy in dogs, accounting for 16%–21% of all skin tumours (Bostock, 1986). They have a variable biological behaviour, ranging from nondisseminating solitary masses to widespread metastasis and, occasionally, systemic disease (Garrett, 2014, Kiupel & Camus, 2019).
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