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1 Gibbs IC Le QT Shah RD Terris DJ Fee WE Goffinet DR. Long-term outcomes after external beam irradiation and brachytherapy boost for base-of-tongue cancers. Int J Radiat Oncol Biol Phys. 57: 489-494 There is no question as to the efficacy of brachytherapy in the management of de novo and recurrent head and neck cancers. It has been shown to contribute to both excellent oncologic outcomes in the upfront setting and durable local control and symptom relief in the recurrent setting.
Original Investigation Elective Radiotherapy Dose and Field in HPV-Associated Oropharyngeal Carcinoma C. Jillian Tsai, MD, PhD; Sean M. McBride, MD, MPH; Nadeem Riaz, MD, MS; Jung J. Kang, MD, PhD; Daniel J. Spielsinger, BS; Todd Waldenberg, BS; Daphna Gelblum, MD; Yao Yu, MD; Linda C. Chen, MD; Kaveh Zakeri, MD; Richard J. Wong, MD, PhD; Lara Dunn, MD; David G. Pfister, MD; Eric J. Sherman, MD; Nancy Y. Lee, MD Full Text Full Text
Abstract It is well understood that the level of molecular oxygen (O2) in tissue is a very important factor impacting both physiology and pathological processes as well as responsiveness to some treatments. Data on O2 in tissue could be effectively utilized to enhance precision medicine. However, the nature of the data that can be obtained using existing clinically applicable techniques is often misunderstood, and this can confound the effective use of the information.
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