Congenital leukemia (CL) is defined as leukemia that is diagnosed within 28 days of birth and the causative mutation develops in utero.[1] Only 20% of CL are lymphoid in origin and usually are characterized by higher white blood cell count, high incidence of central nervous system (CNS) involvement, and strong association with KMT2A, a transcriptional coactivator, which is a positive global regulator of the gene transcription.[2] A 34-year-old female delivered 2,680 g female baby at 38 weeks...
