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Abstract Objective: To investigate whether endoscopic ultrasound (EUS)-guided targeted epinephrine injection is associated with a lower rate of bleeding during endoscopic mucosal resection (EMR). Methods: This retrospective cohort study enrolled consecutive patients undergoing EMR for gastrointestinal lesions ≥1 cm with an EUS-detectable feeding vessel at Zhengzhou Central Hospital between January 2025 and March 2026.
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