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Abstract Understanding whether blood markers maintain stable, individual-specific levels over time is central to systemic homeostasis and precision medicine. While the stability of routine biomarkers is well-established, the long-term dynamics of the broader circulating proteome remain poorly defined. Here we present a 20-year longitudinal cohort study of 1,298 individuals from middle-to-later adulthood to older age.
Abstract Reliable operation of intelligent rotary steerable systems (RSSs) critically depends on the dynamic stability of the bottom-hole assembly (BHA), where high-frequency vibrations can lead to tool malfunction, accelerating structural fatigue, and degrade steering performance under harsh downhole conditions.
ORIGINAL RESEARCH article Volume 16 - 2026 | https://doi.org/10.3389/fonc.2026.1764150 This article is part of the Research TopicNovel Insights into the Tumor Microenvironment's Role in Liver Cancer Occurrence and RecurrenceView all 3 articles 1 Introduction Hepatocellular carcinoma (HCC) is a highly lethal but common malignancy, and its incidence continues to rise globally (1, 2).
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