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While recent studies suggest the prevalence of eosinophilic esophagitis (EoE) may be higher in patients with inflammatory bowel disease (IBD), the determinants of esophageal eosinophilia (EE) and EoE in this population have not been defined. We aim to examine the prevalence of EE and EoE in children with IBD and identify characteristics associated with co-occurring disease.
Abstract Asia is projected to account for the largest proportion of the rising burden of osteoporotic fractures worldwide. Data from the Middle East is scarce. We performed a systematic review on the epidemiology of vertebral and hip osteoporotic fractures in 22 Arab League countries, using Scopus, PubMed, and Embase. We identified 67 relevant publications, 28 on hip and 39 on vertebral fractures.
Introduction Immune checkpoint inhibitors (anti-PD-1 and anti-CLTA-4) are associated with immune-related-adverse-events (irAE). Eosinophilic esophagitis (EoE) is a primary eosinophilic disorder characterized by dysphagia in the presence of pathological eosinophilic infiltration without secondary cause. To our knowledge, this is the first reported case of esophageal eosinophilia (EE) due to combined treatment with ipilimumab/nivolumab.
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