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Articles by R P Gale
Johannes Joseph van Rood Pioneer in immuno-genetics (April 7, 1926-July 21, 2017)
Obituary Leukemia accepted article preview 1 September 2017; doi: 10.1038/leu.2017.278 This is an unedited manuscript that has been accepted for publication. NPG are providing this early version of the manuscript as a service to our customers. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers apply.
Gemtuzumab ozogamicin in acute myeloid leukemia
This is an unedited manuscript that has been accepted for publication. NPG are providing this early version of the manuscript as a service to our customers. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers apply.
Gemtuzumab ozogamicin in acute myeloid leukemia
CD33 is variably expressed on leukemia blasts in almost all patients with acute myeloid leukemia (AML) and possibly leukemia stem cells in some. Efforts to target CD33 therapeutically have focused on gemtuzumab ozogamicin (GO; Mylotarg), an antibody-drug conjugate delivering a DNA-damaging calicheamicin derivative. GO is most effective in acute promyelocytic leukemia but induces remissions in other AML types and received accelerated approval in the US in 2000.
Measurable residual disease testing in acute myeloid leukaemia
There is considerable interest in developing techniques to detect and/or quantify remaining leukaemia cells termed measurable or, less precisely, minimal residual disease (MRD) in persons with acute myeloid leukaemia (AML) in complete remission defined by cytomorphological criteria. An important reason for AML MRD-testing is the possibility of estimating the likelihood (and timing) of leukaemia relapse.
Measurable residual disease testing in acute myeloid leukaemia
This is an unedited manuscript that has been accepted for publication. NPG are providing this early version of the manuscript as a service to our customers. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers apply.
Engraftment syndrome, the Emperor/'s new clothes and the artist formerly known as prince
“Hey man have you heard that new Prince song?” “Who's Prince?” “You know who I mean, The Artist Formerly Known as Prince,Prince” Prince Rogers Nelson In 1993, the vocal artist Prince announced he would henceforth be known by a rune (glyph) combining the astrological symbols for man and woman with a bizarre annotation ( ). He explained his new designator: ‘It is an unpronounceable symbol whose meaning has not been identified. It's all about thinking in new ways, tuning in to a new free-quency’.
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