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Articles by R. Sheldon
PREDICTIVE VALUE OF CLINICAL VARIABLES FOR HYPOTENSIVE SYNCOPE IN PATIENTS WITH BIFASCICULAR BUNDLE BRANCH BLOCK
Previous findings from the Syncope: Pacing or Recording in the Later Years (SPRITELY) trial revealed no significant difference in syncope recurrence among patients with bifascicular block (BFB) regardless of whether they received a pacemaker (PM) or an implantable cardiac monitor (ICM). However, whether baseline clinical variables can predict hypotensive syncope remains unknown.
TILT TESTING OR IMPLANTABLE CARDIAC MONITORING IN THE DIAGNOSIS OF UNEXPLAINED SYNCOPE
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Microwave spectroscopy of positronium atoms in free space
Abstract We report measurements of the positronium (Ps) 2S13→2P23 interval in which atoms traveling in free space were irradiated with microwave radiation generated using a horn antenna. Previous measurements of this transition, performed using atoms in waveguides, exhibited asymmetric and shifted line shapes. In the free-space measurements we report here, much smaller line-shape asymmetry was observed, but with large frequency shifts that varied with the orientation of the horn antenna.
WAIST-HIGH COMPRESSION GARMENTS REDUCE ORTHOSTATIC TACHYCARDIA IN PATIENTS WITH POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME IN A COMMUNITY SETTING
Postural orthostatic tachycardia syndrome (POTS) is a common form of orthostatic intolerance. POTS patients have excessive tachycardia, and debilitating symptoms, when upright. There are no approved medications for use in POTS. Compression garments are a non-pharmacological treatment. We have previously demonstrated a reduction in heart rate (HR) and symptoms with body compression in an acute laboratory setting, using a proof-of-principle waist-high compression garment (WHC).
ATOMOXETINE FOR SUPPRESSION OF VASOVAGAL SYNCOPE: A CLINICAL CASE SERIES
Vasovagal syncope (VVS) is a common clinical condition that lacks effective medical therapies despite being associated with significant morbidity. The norepinephrine transport inhibitors reboxetine, sibutramine, and atomoxetine (Strattera) all prevent the induction of vasovagal syncope on tilt table testing. We hypothesized that atomoxetine would be effective in suppressing syncope in patients with recurrent VVS.
Sex differences in the diagnosis of postural tachycardia syndrome: insights from a cross-sectional community based survey
Background Postural tachycardia syndrome (POTS) is a common form of orthostatic intolerance that primarily affects females of child-bearing age. We compared the diagnostic journey between female and male POTS patients. Methods The “Diagnosis and Impact of POTS” is an IRB approved, patient-community based online self-reported patient survey. Surveyed between Jul2015-Dec2019, 7835 patients with physician-diagnosed POTS were included in this analysis. Continuous data are reported as mean±SEM.
THE POPULATION DENSITY OF MONSTERS IN LOCH NESS1
Corresponding Author Fisheries Research Board of Canada, Marine Ecology Laboratory, Bedford Institute of Oceanography, Dartmouth, Nova Scotia. Present address: Ministry of Natural Resources, Research Branch, Maple, Ontario. Search for more papers by this author
PHARMACOLOGICAL NOREPINEPHRINE TRANSPORTER INHIBITION FOR THE PREVENTION OF VASOVAGAL SYNCOPE: A SYSTEMATIC REVIEW AND META-ANALYSIS
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Vasovagal syncope is a common clinical problem that significantly reduces quality of life yet lacks effective medical therapies. Pharmacological norepinephrine transporter (NET) inhibition increases sympathetic tone, leading to suggestions that it might be able to prevent hypotension and syncope.
HIGH INCIDENCE OF INJURIES IN PATIENTS WITH VASOVAGAL AND BRADYARRHYTHMIC SYNCOPE
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. At least 40% of adults have ≥1 lifetime faint and 20% of adults faint recurrently. Despite its alarm, the incidence of associated injuries is unknown. Purpose: To determine the incidence, severity, and predictors of injuries due to syncope in patients (pts) in 3 syncope clinical trials.
MIDODRINE FOR THE PREVENTION OF VASOVAGAL SYNCOPE: A SYSTEMATIC REVIEW AND META-ANALYSIS
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Vasovagal syncope (VVS) is a common clinical problem that significantly reduces quality of life yet lacks effective medical therapies. Midodrine is an alpha1-adrenergic receptor agonist pro-drug with a short half-life that requires a multiple dose regimen.
THE POPULATION DENSITY OF MONSTERS IN LOCH NESS1
, Sheldon spectrum and the plankton paradox: two sides of the same coin—a trait-based plankton size-spectrum model , The ZooCAM, a new in-flow imaging system for fast onboard counting, sizing and classification of fish eggs and metazooplankton , Some Effects of Eutrophication on Pelagic and Demersal Marine Food Webs , .
VASOVAGAL SYNCOPE PATIENTS HAVE A REDUCED QUALITY OF LIFE AND GREATER PSYCHOLOGICAL DISTRESS COMPARED TO HEALTHY SUBJECTS
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. FiguresPatients with vasovagal syncope (VVS) are highly symptomatic and have a reduced health-related quality of life (HRQoL). There is limited data comparing the HRQoL and psychological profile between VVS patients and healthy individuals.
GENDER DIFFERENCES IN PRESENTATION AND OUTCOME OF VASOVAGAL SYNCOPE: A POST HOC ANALYSIS OF THE PREVENTION OF SYNCOPE TRIALS (POST) I AND II
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. FiguresVasovagal syncope is the loss of consciousness due to decreased heart rate(HR) and blood pressure(BP) from increased parasympathetic tone and concomitant inhibition of sympathetic outflow. It occurs in >40% of Canadians, however differences in presentation and outcomes between male and female patients are not understood.
SYNCOPE: PACING VERSUS RECORDING IN THE LATER YEARS. A RANDOMIZED PRAGMATIC CLINICAL TRIAL OF STRATEGIES OF PERMANENT PACEMAKER VERSUS IMPLANTABLE CARDIAC MONITOR IN OLDER PATIENTS WITH SYNCOPE - Canadian Journal of Cardiology
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. FiguresSyncope with bifascicular block may be caused by intermittent complete heart block, but competing diagnoses may co-exist.
ASSOCIATION OF HOSPITALIZATION WITH FATAL OUTCOMES IN PATIENTS WITH SYNCOPE: A PROPENSITY ANALYSIS
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. FiguresThe proportion of syncope patients who are admitted to hospital from the emergency department (ED) varies significantly. Whether hospital admission affects outcomes is unknown. We assessed the impact of hospital admission on short- and long-term mortality with a propensity analysis of province-wide Alberta data.
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