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Antibody-drug conjugates (ADCs) are an emerging type of biotherapeutics. Consisting of an antibody conjugated to small drug molecules through a variety of linkers, this type of therapeutics is challenging to analyse. Several different linker designs, to limit the release of the cytotoxic drug to as close in proximity to the tumour as possible, and multiple variations of tissue specific antibodies sum up to a chemically very complex set of analytes.
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