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Dear Editor, We read with great interest the study by Kmieć et al. [1] examining whether overnight dexamethasone suppression can improve the interpretability of aldosterone-to-renin ratio (ARR)-based screening for primary aldosteronism in patients receiving renin–angiotensin–aldosterone system–interfering therapy. The protocol addresses a clinically relevant diagnostic barrier that continues to limit the detection of a common and treatable cause of hypertension.
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