DMS-based lipid class separation and selectivity assessment As a starting point, we tested the DMS-based separation of both PG and BMP lipid classes using a pair of isobaric BMP and PG species (BMP 18:1/18:1 and PG 18:1/18:1) in ESI + and ESI- modes, investigating their [M + H]+, [M + NH4]+, [M + Na]+, and [M - H]− ions. However, as shown in Fig. 1 and also partially described by Hankin et al. [6], DMS separation is insufficient for the separation of the tested isobaric PG and BMP lipids.