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Abstract ‘Black box’ deep learning models for medical image interpretation limit clinical trust and analysis of performance degradation. Here we introduce Concept-Level Embeddings for Auditable Radiology (CLEAR), an auditable foundation model based on clinical concepts.
Wei Zhang, Yingqi Zhang, Riga Wu Department of Dermatology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, 010050, People’s Republic of China *These authors contributed equally to this work Correspondence: Riga Wu, Email [email protected] Background: Vitiligo is an acquired autoimmune depigmenting disorder characterized by the loss of functional melanocytes.
Abstract Flavonoids are essential for plant growth and environmental adaptation. Chalcone synthase (CHS) directs metabolic flux into flavonoid biosynthesis, but its catalytic promiscuity limits the biosynthetic efficiency. Although the chalcone isomerase-like protein (CHIL) has been characterized as physically interacting with and regulating CHS, the underlying mechanism remains elusive.
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