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Abstract Background: This study aimed to characterize and compare the dynamic changes in cortical electrophysiological activity during hyperbaric nitrox exposure and subsequent hyperbaric heliox exposure in rats receiving continuous electrocorticographic (ECoG) recording. Methods: Male rats were randomly assigned to the 3% O2–N2, 16% O2–N2, and 100% O2 groups (n=8 per group).
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