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Nanobiotechnology is progressing rapidly, and the last few years have brought a noticeable shift in what the community expects as proof. Advances in nanomaterial design, characterization, and experimental models now make it possible to ask more demanding questions: not only whether a nano-enabled intervention works, but why it works, when it fails, and how its performance depends on context.
1.Farokhzad, O. C. & Langer, R. Impact of nanotechnology on drug delivery. ACS Nano 3, 16–20 (2009).2.Peer, D. et al. Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol. 2, 751–760 (2007).3.Wang, A. Z., Langer, R. & Farokhzad, O. C. Nanoparticle delivery of cancer drugs. Annu. Rev. Med. 63, 185–198 (2012).4.Heath, J. R. & Davis, M. E. Nanotechnology and cancer. Annu. Rev. Med. 59, 251–265 (2008).5.Davis, M. E., Chen, Z. G. & Shin, D. M.
In a conventional SV experiment, a particle in a solution is subjected to three different forces that come into equilibrium and reach terminal velocity in a short period of time. Centrifugal force is directed towards the bottom of the cell and depends on the rotor acceleration (?2r) while the buoyant force and the frictional force act in the opposite direction.
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