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Articles by Robert O'Neill
A Phase 4 Trial to Describe the Immunogenicity, Safety, and Tolerability of MenB‐fHbp in Participants > 10 Years of Age With Asplenia or Complement Deficiency
To the Editor, Invasive meningococcal disease (IMD) is a life-threatening disease caused by Neisseria meningitidis infection [1]. Meningococcal serogroup B (MenB) is the predominant disease-causing serogroup in numerous regions, including the United States and Europe [1]. The MenB-fHbp (Trumenba [bivalent rLP2086]; Pfizer Inc., Philadelphia, PA, USA) MenB vaccine is composed of two lipidated factor H binding protein (fHbp) variants from subfamily A and subfamily B [2].
Ecology & Society: Volume 4, Issue 2
Skip to content Opens in a new window Opens an external site Opens an external site in a new window Response Reasoning without Data, Default Assumptions A response to: Walker and Lonsdale. 2000. "Genetically Modified Organisms at the Crossroads: Comments on "Genetically Modified Crops: Risks and Promise" by Gordon Conway" Suspect Visions A response to: Kotyk. 1999. "No Vision = Wandering in the Wilderness" God, Nature, and Interpretation A response to: Rogers, Roux and Biggs. 2000.
Severe dengue fever with secondary haemophagocytic lymphohistiocytosis
John Moore St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia Department of Haematology, St Vincent's Hospital, Sydney, New South Wales, Australia Blood, Stem Cells and Cancer Research Laboratory, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia Search for more papers by this author
Workers experiencing rising indoor heat exposure, according to new report
Indoor heat exposure is a growing problem for service sector workers, according to a new report by the Harvard Kennedy School-based Shift Project. The report found widespread instances of indoor workers feeling overheated and regularly experiencing temperatures over 80 degrees.
Blue Jays sign star to massive extension
The Toronto Blue Jays sent shockwaves throughout the baseball world Sunday night when news broke that they had agreed to an extension with first baseman Vladimir Guerrero Jr. The extension, first reported by The Athletic’s Ken Rosenthal, is for an eye-popping 14 years at an equally eye-popping $500 million. BREAKING: Vladimir Guerrero Jr. in agreement with Blue Jays on 14-year, $500M extension, pending physical, sources tell @TheAthletic. Story to come.
Cowboys trade for young quarterback
In what has seemingly become a new annual tradition, the Dallas Cowboys traded for a young backup quarterback on Thursday. Last off-season, the team traded for former first-round pick Trey Lance from the San Francisco 49ers. While Lance is still on the roster, quarterback Cooper Rush signed with the Baltimore Ravens, leaving a void in the quarterback room. Thus, the Cowboys turned to the trade market again.
'It's time to move on'
When the Maryland Terrapins knocked off the Colorado State Rams after an enthralling comeback and buzzer beater to advance to the Sweet 16, the mood around the program should have been jubilant. Head coach Kevin Willard advanced past the first weekend for the first time in seven NCAA tournament appearances, and a win over top-seeded Florida would have sent the Terps to the Elite Eight for the first time since 2002.
How understanding the economics of guns can improve public welfare
In 2022, there were more than 48,000 firearm-related deaths in the United States, and firearms were the leading cause of death for Americans under the age of 19. But little is known about how the market for firearms works, and therefore how it could be regulated to improve public welfare. These issues are driving research by economist Luis Armona, assistant professor of public policy at Harvard Kennedy School, who has co-authored two papers on the subject.
Stanford hires former NFL head coach
Days after firing head coach Troy Taylor amid bullying allegations, the Stanford Cardinal have wasted no time hiring a new coach. Cardinal general manager and former NFL quarterback Andrew Luck faced the first significant decision of his executive career and turned to an old friend. According to ESPN’s Pete Thamel, Luck and Stanford are hiring former NFL coach Frank Reich. Sources: Stanford is hiring veteran NFL coach Frank Reich as the school’s interim football coach for 2025 season.
Xavier to hire Richard Pitino as head coach
Rick Pitino took the Big East by storm this season, winning the regular season and conference championships in his second season with the St. John’s Red Storm. The NCAA tournament didn’t go as planned for the Johnnies, who bowed out in the second round after a 75-66 loss to the Arkansas Razorbacks, but their 31-5 record was the best the school had seen in 40 years. Pitino and the Red Storm should be near the top of the Big East again next season, but an intriguing new foe has emerged.
Bengals agree on extensions with Ja'Marr Chase, Tee Higgins
Over the past five years, the Cincinnati Bengals have had one of the NFL’s most exciting and explosive offenses. The Bengals have finished in the top third of the league in offensive yards per game three times in that span. The two outlying seasons featured quarterback Joe Burrow missing significant time with injuries. As long as the Bengals have Burrow, along with wide receivers Ja’Marr Chase and Tee Higgins, they’ll have a chance to compete.
49ers sign veteran quarterback
The San Francisco 49ers have been busy this offseason, overhauling their roster after missing the playoffs for the first time since 2020. On Wednesday, NFL Network’s Ian Rapoport reported that the Niners had found a new backup quarterback, agreeing to a two-year deal with former New England Patriot and Jacksonville Jaguar Mac Jones. Source: Mac Jones has agreed to terms with the #49ers on a 2-year deal for $7M with 5M guaranteed. Max value of $11.5M. A new, experienced backup for Brock Purdy.
Buffalo Bills sign DE Joey Bosa
When the Los Angeles Chargers released defensive end Joey Bosa last week, it seemed like he would head a couple hundred miles north and join the San Francisco 49ers. After all, the Niners have been retooling their roster so far this offseason, and Bosa’s brother Nick Bosa has been with San Francisco since being drafted with the second overall pick in the 2019 NFL Draft. However, it was not to be.
Tampa Bay Buccaneers re-sign WR Chris Godwin
The Tampa Bay Buccaneers have been the NFC South’s team of the 2020s so far, and that’s unlikely to change in 2025. Tampa has won the division for five straight seasons dating back to 2020, as they moved from Tom Brady to Baker Mayfield under center without missing a beat. Tampa’s sustained success is primarily due to wide receivers Mike Evans and Chris Godwin, the two best receivers in franchise history.
Los Angeles Chargers re-sign LB Khalil Mack
After releasing linebacker Joey Bosa early last week, many wondered what the Los Angeles Chargers would look like on the defensive line next season. Bosa’s release seemingly indicated that nine-time Pro Bowler Khalil Mack would be returning with the team, but Mack reportedly had interest from a handful of other teams, including the Chicago Bears. On Monday, Mack put the speculation to rest.
Panthers sign CB Jaycee Horn to huge extension
The Carolina Panthers are a team on the rise. After 2023’s disastrous 2-15 season that saw Frank Reich get fired and rookie quarterback Bryce Young get benched, the team bounced back with a 5-12 performance in their first year under new head coach Dave Caneles. Carolina has a young core on both sides of the ball that they want to continue to grow and develop.
DK Metcalf traded to Steelers, signs four-year extension
The Seattle Seahawks are going to look much different next season. Seattle started last week releasing wide receiver Tyler Lockett, who had been with the team for the past ten seasons. Friday, the Seahawks traded quarterback Geno Smith to the Las Vegas Raiders for a third-round pick. Seattle ended the weekend by trading another offensive stalwart.
Mavericks assistant Alex Jensen leaving team to coach alma mater
It’s been a month to forget for the Dallas Mavericks. From trading Luka Doncic to Kyrie Irving suffering a season-ending torn ACL last week, the hits have kept on coming for the Mavs and their fanbase. On Thursday, the Mavericks got some more unfortunate news. ESPN’s Jeff Borzello and Pete Thamel reported that assistant coach Alex Jensen is leaving the team to become the head coach of the Utah Utes.
Perplexing case of abdominal pain with eosinophilia and fasciitis
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Maxx Crosby signs massive extension with Raiders
As the offseason kicks into gear, the Las Vegas Raiders are one of the most intriguing teams in the NFL. The Raiders shocked many earlier this year when they lured former Seattle Seahawks and USC Trojans head coach Pete Carroll out of retirement and named him the franchise’s new head coach. Holding the sixth pick in the 2025 NFL Draft, there are many paths the Raiders could take. The Raiders are unlikely to take an edge rusher, though.
Royals to honor three-time All-Star, World Series champion
The Kansas City Royals took the MLB world by storm in 2015 when they knocked off the New York Mets to capture their first World Series since 1985. As hard as it is to believe, 2025 marks the tenth anniversary of that World Series winning squad. As such, the Royals will spend much of the 2025 season honoring the team.
Eagles to release six-time Pro Bowler
As the Philadelphia Eagles continue to enjoy the grandeur of being Super Bowl champions, they have already started looking ahead to next season. Like any NFL organization, beloved players who have helped the team for years will naturally start to leave the roster. On Monday, ESPN’s Adam Schefter reported that the Eagles would release cornerback Darius Slay. Eagles are releasing six-time Pro-Bowl CB Darius Slay, per sources.
Three-time NBA All-Star out indefinitely with injury
The Sacramento Kings have undergone more changes this season than any team in the NBA. After getting out to a 13-18 start, the team fired head coach Mike Brown and replaced him with Doug Christie. Then, in February, Sacramento traded 2023 All-Star point guard De’Aaron Fox to the San Antonio Spurs, ending Fox’s seven-and-a-half year run with the team. Despite the circumstances, though, the Kings have kept pushing along.
Travis Kelce makes final decision on playing future
Shortly after the Kansas City Chiefs lost Super Bowl LIX to the Philadelphia Eagles, many wondered if tight end Travis Kelce’s playing career had ended. The 35-year-old tight end struggled to make much of an impact in the blowout loss, hauling in four receptions for 39 yards. In Kansas City’s AFC Championship victory over Buffalo, he had just two catches for 19 yards. The two performances were his lowest playoff outputs since 2020. Kelce put the chatter to rest on Thursday, though.
NFL considering change to regular season overtime rules
As the NFL world turns its attention to Indianapolis for the NFL scouting combine, league executives are also meeting to discuss proposed rule changes for the upcoming season. One change that’s being considered has to do with the regular season’s overtime rule. “It’s time to rethink the overtime rule,” Troy Vincent, the NFL’s vice president of football operations, said Wednesday via ESPN. As it currently stands in the NFL’s regular season, there is one ten-minute overtime period.
'Glad it's over'
The basketball world was shocked earlier this month when the Dallas Mavericks traded star guard Luka Doncic to the Los Angeles Lakers in exchange for Anthony Davis, Max Christie, and a 2029 first-round pick. Not only was the trade head-scratching, but it came out of nowhere. ESPN’s Shams Charania announced the deal shortly after midnight on February 2. Since then, Mavericks general manager Nico Harrison has faced no shortage of criticism for the trade itself and for handling its aftermath.
49ers name new offensive coordinator, quarterbacks coach
The San Francisco 49ers have grown accustomed to success under head coach Kyle Shanahan, From 2019 to 2023, San Francisco went 54-29 and won the NFC West thrice. They also made it to four NFC Championship games and two Super Bowls. While the team has fallen short in the postseason, it has still won eight playoff games during that stretch. The 2024 49ers finished a disappointing 6-11, the second-worst season under Shanahan behind the team’s 4-12 finish in 2018.
Nine-time Pro Bowler retiring from NFL
After a 20-year NFL career, nine-time Pro Bowl offensive tackle Jason Peters has decided to retire. Seahawks general manager John Schneider notified reporters on Tuesday at the NFL Scouting Combine of the 42-year-old’s retirement. ESPN’s Adam Schefter was the first to report the news on X. Nine-time Pro-Bowl OT Jason Peters is expected to retire after playing 19 NFL seasons and 248 NFL games, Seahawks GM John Schneider told reporters at the combine.
Abdul Carter makes decision on NFL Combine workouts
Former Penn State defensive end Abdul Carter won’t work out at the NFL Combine this week. Carter, projected to be a top-five pick in April’s NFL Draft, is working his way back from a shoulder injury suffered late in Penn State’s season. ESPN’s Adam Schefter first reported the news from Carter’s agents Drew Rosenhaus and Robert Bailey. Penn St. DE and potential No. 1 pick Abdul Carter will not work out at the combine because he has not fully recovered from the shoulder injury he suffered vs.
Longest-tenured defensive player leaving Carolina Panthers
The Carolina Panthers were one of the NFL’s surprise teams last season, going 5-12 and finishing third place in the NFC South in their first season under head coach Dave Caneles. While five wins may not seem like much, it was night and day from Carolina’s disastrous 2-15 finish in the 2023 season. More impressively, the Panthers got to five wins without one of their defensive leaders. Linebacker Shaq Thompson tore his Achilles in September and appeared in just four games on the season.
Joel Embiid, 76ers considering knee surgery for star
This season has been one to forget for the Philadelphia 76ers. With 16 games to play, Philadelphia currently holds the 12-seed in the Eastern Conference at 20-36. While the Sixers could still catch the 10-seed Chicago Bulls and sneak into the Play-In Tournament, it’s a staggering fall for the team that has finished over .500 every season since 2017-18, winning 50 or more games in four of the seasons.
Yankees extend manager Aaron Boone
The New York Yankees have agreed to a two-year contract extension with manager Aaron Boone, the team announced Thursday. The 51-year-old has managed the club since the 2018 season. The New York Yankees today announced that they have signed Manager Aaron Boone to a two-year contract extension through the 2027 season. pic.twitter.com/t9u7fWfzVz — New York Yankees (@Yankees) February 20, 2025 Boone’s time as manager of the Yankees has been successful, though not without its criticisms.
Cubs sign two-time All-Star third baseman
When the Chicago Cubs traded for Houston Astros outfielder and four-time All-Star Kyle Tucker in December, it seemed to indicate the team would spend the rest of the offseason being competitive on the trade and free agency markets. Fast forward two months, and the roster looks similar to when Tucker was acquired. The Cubs could not swing a trade for a starting pitcher and missed out on free-agent third baseman Alex Bregman.
ACC team hires ex-head coach as offensive coordinator
The Virginia Tech Hokies went 6-7 in the 2024 season, with a season-ending 24-10 loss in the Dukes Mayo Bowl pushing the team under .500. Virginia Tech’s offense was inconsistent, averaging 367 yards per game and finishing in the lower half of ACC teams. While the Hokies seemed poised to run things back with offensive coordinator Tyler Bowen, that plan hit a snag two weeks ago when Bowen left Blacksburg to become Ohio State’s new offensive line coach.
Yankees star shares unfortunate injury news
The New York Yankees had their best season in 15 years in 2024, winning the American League pennant and playing in the World Series for the first time since 2009. While they lost in five to the Los Angeles Dodgers, the season was a success. Entering the 2025 season, the Yankees are one of the favorites to win the AL again. Despite losing Juan Soto to the rival Mets, unlike most AL teams, the Yankees were active in free agency and the trade market.
Boston Red Sox sign Alex Bregman
The Boston Red Sox have reportedly agreed to a contract with free agent third baseman Alex Bregman. News of the contract broke late Wednesday night, with The Athletic’s Chandler Rome being the first to report. Free-agent third baseman Alex Bregman in agreement with the Boston Red Sox, source tells @TheAthletic — Chandler Rome (@Chandler_Rome) February 13, 2025 Rome followed up shortly after, saying the contract was for three years and would pay Bregman $120 million.
Kevin Durant makes NBA history in loss
Phoenix Suns forward Kevin Durant has racked up no shortage of accolades throughout his illustrious NBA career. The 36-year-old has been NBA MVP (2014), a two-time NBA Champion (2017, 2018), a two-time NBA Finals MVP, and a 15-time NBA All-Star. Durant achieved another accolade Tuesday night in Phoenix’s 119-112 loss to the Memphis Grizzlies. With a free throw in the third quarter, he became the eighth player in NBA history to score 30,000 points.
MLB world reacts to major Clayton Kershaw news
The Los Angeles Dodgers have been Major League Baseball’s busiest team this offseason. Los Angeles dominated the free agent market, signing pitchers Blake Snell, Rori Sasaki, Tanner Scott, and Kirby Yates. The team also added outfielders Michael Conforto, Teoscar Hernandez, and infielder Hyeseong Kim. Through it all, there was one missing piece to LA’s offseason. Starting pitcher Clayton Kershaw has been with the team since his 2008 MLB debut.
Angels sign four-time All-Star reliever
It’s been an interesting offseason for the Los Angeles Angels. The team has made some moves to throw their hat into the playoff race this offseason. They traded for outfielder and former World Series MVP Jorge Soler in November. Later in November, they signed catcher Travis D’Arnaud. Soler, D’Arnaud, and a healthy Mike Trout should provide a major boost to the team’s offense. On Tuesday, the Angels struck with another big move.
Big 12 team names new offensive coordinator
The Kansas State Wildcats have been among the Big 12’s most successful teams over the past three years. Head coach Chris Klieman’s bunch won at least nine games per season in that time, with a 2022 Big 12 Championship and Sugar Bowl appearance leading the accolades. The 2024 season saw the Wildcats finish 9-4. Kansas State’s 426 yards per game on offense put them in the top third of the Big 12, as co-offensive coordinators Matt Wells and Conor Riley worked together to keep the ball moving.
MLB world reacts to fan favorite's return to Dodgers
The Los Angeles Dodgers have had one of the busiest offseasons in Major League Baseball. The defending champions cleaned up the free agent market this winter, signing free agent pitchers Blake Snell, Rori Sasaki, Tanner Scott, and Kirby Yates to significant contracts. Over the weekend, though, Los Angeles turned its attention a position player. Utility fielder and fan favorite Enrique Hernandez announced on his social media that he would be returning for the Dodgers for another season.
Chargers add former ACC defensive coordinator to staff
While many NFL coaching staffs include former college assistants, few teams embrace this concept more than the Los Angeles Chargers. It makes sense as to why the Chargers operate the way they do. Head coach Jim Harbaugh has spent 16 seasons as a head coach at the collegiate level. He has no shortage of connections across the country. When Harbaugh took the Chargers job last offseason, he brought multiple staffers from the Michigan Wolverines, where he had coached for the previous eight seasons.
Ex-Super Bowl champion, scoring leader announces retirement
As the football world prepares for Super Bowl LIX in New Orleans, a prolific postseason performer has announced his retirement. Longtime Green Bay Packers kicker Mason Crosby announced Tuesday on his radio show that he would officially step away from the NFL. #TheMasonCrosbyShow ð¨ BREAKING! ð¨ @crosbykicks2 announces his retirement from the NFL.
Top free agent pitcher signs with Detroit Tigers
The Detroit Tigers surprised many baseball fans last season when they captured one of the American League Wild Cards and made the postseason for the first time in a decade. Detroit swept the Houston Astros in the Wild Card series and took the Cleveland Guardians to five games in the ALDS before falling short. Some fans wondered if Detroit planned to add to its roster this offseason in an effort to return to the postseason. On Sunday, fans got their answer.
NBA breakout star done for season
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Atlanta Hawks star to miss rest of season with injury
The Atlanta Hawks have made the NBA playoffs in each of the past three seasons, but extending the streak to four years may prove challenging. Atlanta has a 22-25 record and is ninth in the Eastern Conference. They are three games ahead of the Philadelphia 76ers for the final playoff spot and just two games behind the six-seed Miami Heat. Jumping Miami would see Atlanta avoiding the Play-In Tournament, where the Hawks have never played.
Former NBA All-Star signs with G-League team
Two-time NBA All-Star guard Isaiah Thomas is looking to return to the league. On Monday, Thomas took the first step, re-joining the Salt Lake Stars, the G-League affiliate of the Utah Jazz. ESPN’s Shams Charania reported the news first. Two-time All-Star Isaiah Thomas is pursuing another NBA return, signing into the G League and rejoining the Utah Jazz’s Salt Lake City affiliate, sources tell ESPN. Last season, Thomas averaged 33 points in four G League games en route to a call up to the Suns.
Cubs acquire former All-Star closer
After back-to-back 83-79 finishes, the Chicago Cubs seemed destined to improve their roster this offseason. While they missed out on top free agents Juan Soto, Max Fried, and Roki Sasaki, Chicago has turned to the trade market to bolster their squad. In December, the teams agreed to send Houston outfielder and three-time All-Star Kyle Tucker to the Cubs in exchange for third baseman Isaac Parades and a pair of starting pitchers. On Sunday, the Cubs and Astros reached an agreement on another trade.
Braves sign All-Star outfielder
The Atlanta Braves became the latest Major League Baseball team to add an All-Star via free agency. On Thursday, Atlanta agreed to a three-year contract with outfielder Jurickson Profar. The team announced in a press release that the three-year deal was worth $42 million. #Braves Sign Jurickson Profar: pic.twitter.com/KdN2I1OdyX — Atlanta Braves (@Braves) January 23, 2025 Profar signed with the Texas Rangers as an international free agent in 2009 and made his major league debut in 2012 at 19.
Dodgers hire former Manager of the Year
The Los Angeles Dodgers have been one of MLB’s busiest teams this offseason, signing multiple top free agents and putting themselves in a position to return to the World Series. Los Angeles has made another acquisition, though it wasn’t a player this time. The Tulsa Drillers, LA’s Double-A team announced that former Cleveland Guardians and Seattle Mariners manager Eric Wedge would manage the team in 2025.
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